We are the global leader in genomic diagnostics, translating complex genetic data into actionable insights that transform patient care. Our team combines cutting-edge bioinformatics with clinical expertise to deliver accurate, scalable solutions for healthcare providers worldwide. As we expand our platform’s capabilities, we’re seeking a senior engineer to optimize our bioinformatics pipelines and drive innovation in precision medicine.

The Role

As a Senior Software Engineer/Bioinformatician, you’ll lead technical initiatives to enhance the speed, accuracy, and scalability of our production diagnostics platform. You’ll architect robust bioinformatics solutions, mentor teammates, and ensure compliance with clinical standards (CAP/CLIA) while advancing our mission to improve patient outcomes through genomics.

What You’ll Do

1. Design & Optimize: Improve variant calling algorithms, pipeline efficiency, and infrastructure (AWS/Kubernetes) for NGS/non-NGS assays.
2. Lead Validations: Spearhead analytical validation efforts for pipeline upgrades and new products.
3. Elevate Standards: Establish software engineering best practices in a regulated (CAP/CLIA) environment.
4. Solve Complex Problems: Troubleshoot wet/dry-lab issues and optimize Bayesian/ML-based bioinformatics applications.
5. Collaborate Cross-Functionally: Partner with bioinformaticians, DevOps, and lab teams to align technical solutions with clinical needs.

What We Value

1. Technical Depth: Expertise in pipeline scalability, variant calling (especially structural variants), and modern software practices.
2. Ownership: Ability to lead high-stakes projects where decisions impact diagnostic accuracy and timelines.
3. Resourcefulness: Creative problem-solving in resource-constrained environments.
4. Compliance Mindset: Familiarity with CAP/CLIA inspections and assay validation.

Tech Stack & Requirements

1. Core: Python, AWS, Docker, Kubernetes, Helm, CI/CD, automated testing
2. Bioinformatics: Samtools, GATK, Picard, VCFtools, BEDtools
3. Stats/ML: Bayesian methods, machine learning applications in genomics
4. Experience: 5+ years in production software (regulated industry preferred); PhD strongly preferred

Key Responsibilities

1. Deliver cost-efficient, reliable pipelines meeting clinical-grade standards.
2. Write high-quality, documented code peer-reviewed by teammates.
3. Mentor colleagues to elevate team-wide technical expertise.
4. Ensure modular, evolvable bioinformatics software for future innovation.

Why Join Us?

1. Impact: Your work directly improves diagnostic accuracy for patients globally.
2. Growth: Lead initiatives at the forefront of genomic medicine.
3. Culture: Collaborative, mission-driven team with low ego and high psychological safety.
4. Benefits: Competitive salary, equity, 401(k), top-tier healthcare, flexible PTO.

Ideal Candidate

You’re a PhD-level engineer/bioinformatician with deep expertise in NGS pipelines, variant calling, and regulated environments. You thrive when trusted to solve hard problems and inspire teams through technical leadership.

Apply today to build the future of genomic diagnostics.